Spreadsheets are a type of software for handling large amounts of data, often numerical. They consist of a grid of cells, although a spreadsheet files often contain more than one sheet.
A cell is where a row and column cross to make a box for you to enter data in.
Rows go horizontally across the screen.
Columns go vertically down the screen.
A cell gets its name from the column and row it's in. For example, A6 (Column A, Row 6).